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Pharmacology Services

Frontier Research Labs brings several years of experience in following areas of research  in Pharmacology at B.Pharmacy, M. Pharmacy & Ph.D level research.Projects.  Our research advisors helps you at each and every steps of the work.

You may choose any activity and suitable model for your research work from below list-

Anti Diabetes Activity

In Vivo Activity-

Alloxan induced diabetic  model

Streptozotocin induced diabetic  model

In Vitro Activity- 

Alpha-galactosidase inhibitory activity

Alpha-Amylase inhibitory activity

Alpha-glucosidase activity

Glucose uptake studies

Gene expression studies (PPARγ, GLUT-4 etc)

Anti cancer Activity

In Vivo Activity-

DLA/EAC induced ascitic tumor model

Mouse Forestomach Tumorigenesis

 

In Vitro Activity-

Clonogenic assay

Cytotoxicity assay by MTT/SRB/Trypan blue

TUNEL assay

Endonuclease assay

Apoptosis – Nuclear staining with DAPI

Alkylating activity assay

DNA fragmentation analysis / DNA ladder assay

Cancer specific gene expression analysis

Hepatoprotective Activity

In Vivo Activity-

Paracetamol induced Hepatoptotoxicity  study

Rifampicin induced Hepatoptotoxicity  study

In Vitro Activity-

Hepatoprotective study

Gene expression studies

 

Antioxidant Activity

In Vivo Activity-

Antioxidant status in by hepatic injury model

Antioxidant status in tumor bearing model

In Vitro Activity-

Ferric ion reducing power assay

DPPH

Nitric Oxide scavenging assay

Lipid peroxidation inhibitory activity

 Total Phenolic and Flavonoid content estimation

Total Antioxidant capacity

Scavenging of Hydrogen Peroxide

Scavenging of ABTS radical cation Assay

 

Anxiolytic, Analgesic  & Inflammation Activity

In Vivo Activity-

Elevated Plus maze Method

Radiant heat method

Tail immersion test

Writhing test

Paw edema model

Oxazolone-induced ear edema in mice

Carbon clearance assay model

Cellular Immune Response Model

Humoral Immune Response Model

Neutrophil Adhesion Test Model

In Vitro Activity-

Phagocytic assay & Proliferation assay

NO and TNF inhibitory studies

Inhibition of protein denaturation

Proteinase inhibitory action

Analysis of markers like COX-1, COX-2, PGE-2, Interleukin

 

Other Activity

Different wound healing models

Anti microbial activity by Zone of inhibition and MIC determination

Antibiotic sensitivity testing

Hypercholesterolemia

Arthritis & Osteoporosis

Allergy & Antitussive

Psoriasis

Immunomodulatory

Skin whitening

Skin irritation (Dermal toxicity)

Genotoxicity

Enzyme and Immunoassays (ELISA)

Gout and Urolithosis

Stability studies as per ICH

Accelerated stability studies

Long term stability studies.

Photo stability studies

Forced degradation studies

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